SKU: C206  / 
    CAS Number: 80451-05-4

    Cecropin B

    Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and antibacterial activities. It is also active against fungi, and has cytotoxic effects on cancer cell lines.

    TOKU-E also offers:
    Mechanism of ActionThe antibacterial mode of action for Cecropins is pore-formation based, in which an antimicrobial peptide inserts itself into the bacterial membrane and allows ions to flow freely through, resulting in cell depolarization and death.
    Molecular FormulaC176H301N51O42S
    ReferencesChen, H. M., Wang, W., Smith, D., & Chan, S. C. (1997). Effects of the anti-bacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria, and cancer cells. Biochimica Et Biophysica Acta (BBA) - General Subjects, 1336(2), 171-179. doi:10.1016/s0304-4165(97)00024-x