Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 µg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. FASII is essential to bacterial cell viability and is a promising target for the development of novel antibiotics.
Bischloroanthrabenzoxocinone is soluble in ethanol, methanol, DMF and DMSO.
Bischloroanthrabenzoxocinone is soluble in ethanol, methanol, DMF and DMSO.