• Tetramisole hydrochloride

click on thumbnail to zoom
SKU: T061

Size  
Quantity:
 
Price: make selection(s)
Description
Tetramisole hydrochloride (levamisole, ergamisol) is an alkaline phosphatase inhibitor with antihelminthic and anticancer properties.
 

    CAS Number

    5086-74-8

    Molecular Formula

    C11H12N2S · HCl

    Molecular Weight

    240.75

    Mechanism of Action

    Tetramisole HCl inhibits parasitic worm growth by acting as an agonist to nicotinic acetylcholine receptors leading to paralysis. The mechanism of action for anticancer activity is unknown.

    Spectrum

    Tetramisole HCl inhibits kidney, liver, placenta, bone, and tumor alakaline phosphatases.

Specifications

    Appearance

    White or pale yellow crystalline powder

    pH

    4.0 - 5.5

    Melting Point

    262 - 267┬░C

    Assay

    98.0 - 101.0%

    Loss on Drying

    Not more than 0.5%

    Sulfated Ash

    Not more than 0.5%

References

    References

    Artwohl, Michaela. "Levamisole Induced Apoptosis in Cultured Vascular Endothelial Cells." British Journal of Pharmacology 131.8 (2000): 1577-583. Web.

Other Items In This Category