• Quinolactacin A1 packaged and labeled in glass vial.

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SKU: Q006

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Description
Quinolactacin A1 is the dominant analogue of a family of quinolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to inhibit acetylcholinesterase and TNF production.

Quinolactacin A1 is soluble in ethanol, methanol, DMF and DMSO.  

    CAS Number

    815576-68-2

    Molecular Formula

    C16H18N2O2

    Molecular Weight

    270.3

Specifications

    Appearance

    White Powder

References

    References

    Biosynthesis of quinolactacin A, a TNF production inhibitor. Sasaki T. et al. J Antibiot. 2006, 59, 418.

    Quinolactacins A1 and A2, new acetylcholinesterase inhibitors from Penicillium citrinum. Kim W.G. et al. J Antibiot. 2001, 54, 831.

    Quinolactacins A, B and C: novel quinolone compounds from Penicillium sp. EPF-6. I. Taxonomy, production, isolation and biological properties. Kakinuma N. et al. J Antibiot. 2000, 53,1247.

    Clark B. et al. Quinolactacins revisited: from lactams to imides and beyond. Org Biomol Chem. 2006, 4, 1512.

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