• Paclitaxel (Taxol) packaged and labeled.

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SKU: P045

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Description

Paclitaxel is a unique anti-tumor agent derived from the bark of the Pacific Yew tree. Pacitaxel is sparingly soluble in ethanol, DMSO, and DMF.

    CAS Number

    33069-62-4

    Molecular Formula

    C47H51NO14

    Molecular Weight

    853.91

    Mechanism of Action

    Paclitaxel prevents tumor growth by stabilizing microtubules during mitosis in the G2/M growth phase leading to cell death.

    Storage Conditions

    2-8°C

    Tariff Code

    2932.99.6100

Applications

    Cancer Applications

    Paclitaxel can be used to study effects on actively dividing tumor cells.

Specifications

    Form

    Powder

References

    References

    Fiser, Andras, et al. "Insights into the Mechanism of Microtubule Stabilization by Taxol." PNAS 103.27 (2006): 10166-0173. Pnas.org. Web. 21 June 2013.

    Horwitz, S. B. "Taxol (paclitaxel): Mechanisms of Action." Annals of Oncology 6th ser. 6 (1994): n. pag. Ncbi.gov. Web. 21 June 2013

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