• Nystatin A1, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: N044

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Nystatin is polyene antifungal containing a conjugated tetraene and a diene, isolated as a complex of three components A1, A2 and A3 from Streptomyces noursei and first reported in 1950. Nystatin is an established bioprobe and widely-used antifungal reagent with over 4,000 literature citations.

Nystatin A1 is soluble in DMF or DMSO, and moderately soluble in methanol or ethanol. Poor water solubility.

    CAS Number

    1400-61-9

    Molecular Formula

    C47H75NO17

    Molecular Weight

    926.1

    Mechanism of Action

    Nystatin, like most polyene antifungals, binds to sterols in the fungal cell membrane leading to formation of ion channels in the wall, ion imbalance and cell death.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Yellow solid

References

    References

    Two antifungal agents produced by a soil actinomycete. Hazen E.L. & Brown R. Science 1950, 112, 423.

    Macrolide antibiotic studies. XVI. The structure of nystatin. Chong C.N. & Rickards R.W. Tet. Lett. 1970, 59, 5154.

    The structure of nystatin A3, a component of nystatin complex. Zielinski J. et al. J. Antibiot. 1988, 41, 1289.

Other Items In This Category