• Lincomycin packaged and labeled in glass vial.

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SKU: L014

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Description
Lincomycin is a polar, water soluble, broad spectrum antibiotic first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. Lincomycin was the first of a unique structural class, the lincosamides, containing a rare amino acid, 4-propyl-N-methylproline, coupled to an equally rare aminomethylthio-octopyranoside sugar. Lincomycin and semi-synthetic analogues are often incorrectly considered to be aminoglycosides but share little or no structural similarity. Lincomycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin has been extensively studied with over 7,000 literature citations.

Lincomycin is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    154-21-2

    Molecular Formula

    C18H34N2O6S

    Molecular Weight

    406.5

    Mechanism of Action

    Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Lincomycin, a new antibiotic. I. Discovery and biological properties. Mason D.J. et al. Antimicrob. Agents Chemother. 1962, 1963, 554.

    Biological activity of the lincomycin related antibiotics. Mason D.J. & Lewis C. Antimicrob. Agents Chemother. 1964, 10, 7.

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