• Enniatin A1, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: E036

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex.

Enniatin A1 is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. 

    CAS Number

    4530-21-6

    Molecular Formula

    C35H61N3O9

    Molecular Weight

    667.9

    Storage Conditions

    -20°C

Specifications

    Appearance

    White powder

References

    References

    Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria. Gaumann E. et al. , Experientia 1947, 3, 202.

    "Sandwich" complexation in cyclopeptides and its implications in membrane processes. Ivanov V.T. Ann. N. Y. Acad. Sci. 1975, 264, 221.

    Interaction of cyclic peptides and depsipeptides with calmodulin. Mereish K.A. et al. , Pept. Res. 1990, 3, 233.

    Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae. Hiraga K. et al. , Biochem. Biophys. Res. Commun. 2005, 328, 1119.

    Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Dornetshuber R. et al. , Chem. Res. Toxicol. 2007, 20, 465.

Other Items In This Category