• Azidamfenicol packaged and labeled in glass vial.

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SKU: A141

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Description
Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Azidamfenicol has received little research attention with only a few literature citations.

Azidamfenicol is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    13838-08-9

    Molecular Formula

    C11H13N5O5

    Molecular Weight

    295.3

    Mechanism of Action

    Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    1-p-Nitrophenyl-2-azidoacetylaminopropane derivatives. Meiser W. & Domagk G. 1959 US Patent 2,882,275.

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