• 4-epitetracycline HCl, EvoPure packaged and labeled.

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SKU: T053

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Description

4-Epitetracycline HCl, EvoPure® is a highly purified hydrochloride salt form of 4-Epitetracycline.  Under acidic conditions, Tetracycline undergoes an epimerization at the fourth carbon, producing a mixture of Tetracycline and 4-Epitetracycline.  This EvoPure product is soluble in water.

For other Tetracycline products, click here.

    CAS Number

    23313-80-6

    Molecular Formula

    C22H24N2O8 · xHCl (lot specific)

    Molecular Weight

    444.43 g/mol (Free base. Actual molecular weight shown on lot specific certificate of analysis).

    Mechanism of Action

    Tetracycline inhibits the growth of Gram-positive and Gram-negative bacteria by disrupting codon-anticodon interactions at the ribosome, thus blocking protein synthesis. Specifically, Tetracycline binds to the 30S ribosomal subunit and blocks the attachment of charged aminoacyl-tRNA to the A site on the ribosome, preventing peptide elongation.

    Storage Conditions

    -20°C. Protect from moisture and light

    Tariff Code

    2941.30.0000

    Spectrum

    Effective against Gram-positive and Gram-negative bacteria, and Mycoplasma.

Applications

    Application

    4-Epitetracycline HCl, EvoPure® can be used as an analytical standard.

Specifications

    Form

    Powder

    Appearance

    Yellow Solid

    Source

    Synthetic

Technical Data

HPLC, NMR, FTIR, and MS analysis may be available. For more info, please email [email protected].

References

    References

    Mazur X, Eppenberger HM, Bailey JE and FUssenegger M (2000)  A novel autoregulated proliferation-controlled production process using recombinant CHO cells.   Biotechnol and Bioeng.  65(2):144-150

    Fernandez AA, Noceda VT, Carrera ES (1969)  Simultaneous separation and quantitative determination of tetracycline, anhydrotetracycline, 4-epitetracycline, and 4-epi-anhydrotetracycline in degraded tetracyclines by thin-layer chromatography. J. Pharm. Sci. 58(4):443-446

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