• 4-Aminobenzoic acid packaged and labeled.

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SKU: A049

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Description

4-Aminobenzoic acid (PABA, para-aminobenzoic acid) is a B vitamin derivative and is used by bacteria to synthesize folate (vitamin B9), an essential vitamin for bacteria and humans. 4-Aminobenzoic acid is sparingly soluble in water at 6.11 mg/mL.

    CAS Number

    150-13-0

    Molecular Formula

    C7H7NO2

    Molecular Weight

    137.14

    Storage Conditions

    Ambient, air and light sensitive

    Tariff Code

    2922.49.1000

Applications

    Microbiology Applications

    Folate (vitamin B9) plays an essential role in the synthesis, repair, and methylation of DNA. In addition, many sulfonamide antibiotics inhibit dihydropteroate synthetase, an enzyme involved in the folate synthesis pathway.

Specifications

    Appearance

    White crystalline powder

    Impurity Profile

    Volatile Diazotizable Substances: Not more than 0.002%
    Ordinary Impurities: Not more than 1.0%
    Limit of Aniline: Not more than 10ppm
    Limit of p-Toluidine: Not more than 10ppm

    Melting Point

    186-189°C

    Loss on Drying

    ≤0.2%

    Residue On Ignition

    ≤0.1%

    Heavy Metals

    ≤0.002%

References

    References

    Basset, Gilles. "Folate Synthesis in Plants: The P-aminobenzoate Branch Is Initiated by a Bifunctional PabA-PabB Protein That Is Targeted to Plastids." PNAS 101.6 (2004): 1496-501. Ncbi.gov. Web. 19 Nov. 2012.

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