Sulfamerazine is a bacteriostatic sulfonamide antibiotic. Sulfamerizine is essentially insoluble in water at 0.20 mg/mL.TOKU-E offers two forms of sulfamerazine: sulfamerazine (S033) and sulfamerazine sodium (S059).
|Mechanism of Action||Like most sulfonamides, sulfamerazine inhibits folic acid synthesis by acting as a competitive inhibitor of dihydropteroate synthetase, an enzyme found in the folic acid synthesis pathway.|
|Spectrum||Sulfamerazine is a broad spectrum antibiotic targeting a wide range of Gram positive and Gram negative bacteria.|
|Impurity Profile||Impurity UN1| Sulphanilamide|63-74-1|C6H8N2O2S|172.20||
|References||Henry, Richard J. "The Mode of Action of Sulfonamides." Bacteriology Reviews (n.d.): 175-84. www.ncbi.gov. Web. 27 Aug. 2012.|