Antiparasitics

Antimycin A4

Antimycin A4 is the most polar of the major components of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A3. Antimycin A4 exhibits broad biological activity as an antifungal, anthelmintic,...

View Details

Enniatin A

Enniatins are a family of depsipeptide ionophores, produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus...

View Details

Antimycin

Antimycin (syn: Antimycin A) is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogs in the...

View Details

Enniatin A1

Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus...

View Details

Enniatin B

Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus...

View Details

Enniatin

Enniatins are a complex of depsipeptides produced by several Fusarium species. Typically, the complex contains 4 major components: A, A1, B and B1 together with minor amounts of enniatins C, D, E and F. The enniatins act as ionophores. Recently their...

View Details

Rifampicin

Rifampicin (syn: Rifampin) is a semisynthetic antimicrobial compound derived from rifamycin SV and originally developed by the Lepetit group in 1965.  Rifampicin shows activity against Gram-positive bacteria, particularly mycobacteria like...

View Details

Piericidin A

Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces species.Piericidin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.Mechanism of ActionPiericidin A is a specific, potent...

View Details

Prodigiosin

Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant...

View Details

Sulfadoxine (Sulphadoxine)

Sulfadoxine is a sulfonamide antibiotic frequently used for the treatment of malaria and bacteria that cause urinary and respiratory tract infections. Sulfadoxine is also routinely used in combination for malaria infections when used in combination with...

View Details

Amodiaquine Hydrochloride

Amodiaquine Hydrochloride is a synthetic,4-aminoquinoline compound with anti-malarial and anti-inflammatory properties.  It is a histamine-N-methyltransferase inhibitor that was developed in 1948.  Amodiaquine Hydrochloride is a congener of...

View Details

Chloroquine Phosphate

Chloroquine Phosphate is a 4-aminoquinoline compound used to inhibit growth of malarial parasites. It is a weak intercalating agent. Chloroquine Phosphate can be used as a DNA interacalator and can be used to increase transfection efficiency. It has...

View Details