Chemotherapeutics

Amicoumacin B

Amicoumacin B is a complex antibiotic and isocoumarin produced by Bacillus subtilis. This natural product, a fungal metabolite, is a quorum-sensing inhibitor with activity against Chromobacterium violaceum. It reduces the expression of C. violaceum...

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Pactamycin

Pactamycin (syn: Pactacin) is a unique type of highly-substituted aminocyclitol produced by Streptomyces sp. which is a potent inhibitor of translation in eukaryotes, bacteria and archaea, active against Gram-positive and Gram-negative bacteria. ...

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Aspergillin PZ

Aspergillin PZ is an isoindole metabolite isolated from Aspergillus awarori by activity-guided fractionation and purification. Aspergillin PZ adversely affects the hyphae and spores of P. oryzae, a nitrogen-fixing bacterium. Aspergillin PZ has weak...

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Aminopterin

Aminopterin is a 4-amino derivative of folic acid and a folic acid antagonist. It is a synthetic derivative of pterin. It has both mmunosuppressive properties and anti-cancer properties and can be used for apoptosis research. The compound was discovered...

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Banksialactone A

Banksialactone A is the simplest and major analogue of a family of isochromanones isolated from an Australian fungus,Aspergillus banksianus, by researchers at Macquarie University, Australia and Microbial Screening Technologies in 2018. While...

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Methotrexate Sodium

Methotrexate Sodium is a selective agent for dihydrofolate reductase (DHFR)- transfected cells and a nucleic acid synthesis inhibitor in protein expression systems. It is commonly used as an ancillary material in upstream biomanufacturing applications...

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Dihydrotanshinone I

Dihydrotanshinone I is one of many bioactive products isolated from Salvia miltiorrhiza, a well-known traditional Chinese medicinal plant. It's primary promise lies in its anticancer activity, but it has been found to be active against gram-positive...

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Embelin

Embelin is a benzoquinone derivative from the Japanese Ardisia herb. It is a cell-permeable, small-molecule inhibitor of apoptosis regulator proteins. It is a promising start to a new class of anticancer drugs that target apoptosis regulator proteins. It...

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Gageostatin A

Gageostatin A is an antimicrobial peptide (AMP) isolated from a marine strain of Bacillus subtilis. Gageostatin A is a linear lipopeptide composed of 7 peptides, and has shown initial bioactivity against pathogenic fungi, Gram-positive and Gram-negative...

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Niclosamide monohydrate

Niclosamide is commonly known as an antihelminthic drug used in the treatment of tapeworms. It has also been used as a molluscicide in water treatment, and more recently there are several reports of niclosamide showing anticancer activity. TOKU-E...

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Niclosamide anhydrous

Niclosamide is commonly known as an antihelminthic drug used in the treatment of tapeworms. It has also been used as a molluscicide in water treatment, and more recently there are several reports of niclosamide showing anticancer activity. TOKU-E...

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Cecropin B

Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and...

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