• Sulfadiazine packaged and labeled.

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SKU: S012

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Description

Sulfadiazine is a bacteriostatic sulfonamide antibiotic and is sparingly soluble in aqueous solution (0.077 mg/mL).

    CAS Number

    68-35-9

    Molecular Formula

    C10H10N4O2S

    Molecular Weight

    250.28 g/mol

    Mechanism of Action

    Sulfadiazine interferes with the folic acid metabolism in bacteria by inhibiting p-aminobenzoic acid, a major component in the folic acid cycle.

    Storage Conditions

    2-8 °C , protect from light

    Tariff Code

    2935.00.4200

    Spectrum

    Sulfadiazine is a broad spectrum antibiotic targeting a wide range of gram positive and gram negative bacteria especially those which cause urinary tract infections.

Applications

    Microbiology Applications

    Sulfadiazine is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive and gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:

    • Neisseria meningitidis 0.5 µg/mL – 200 µg/mL
    • For a complete list of sulfadiazine MIC values, click here.

Specifications

    Form

    Powder

    Appearance

    White or slightly yellow powder.

    Source

    Synthetic

    Impurity Profile

    Impurity A| Pyrimidin-2-amine|109-12-6|C4H5N3|95.1| Impurity B| 4-Aminobenzenesulfonic Acid (Sulphanilic Acid)|121-57-3|C6H7NO3S|173.19| Impurity D| 4-Aminobenzenesulfonamide (Sulfanilamide)|63-74-1|C6H8N2O2S|172.20| Impurity UN1| N4-Acetylsulfadiazine|5572-57-6|C12H12N4O3S|292.31|

    Melting Point

    252-256 °C

References

    References

    "Sulfadiazine: Mechanism of Action." Cancer News Network. N.p., 2009. Web. 21 Aug. 2012.

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