Hygromycin B, EvoPure®is a high purity (>99.0%) form of hygromycin B. Hygromycin B is a unique aminoglycoside antibiotic derived from Streptomyces hygroscopicus and is routinely used as a selective agent in cell culture or microbiology applications to isolate hygromycin B resistant cells after transfection or transformation, respectively.
Custom Manufacturing and Testing: TOKU-E Company is able to perform specific tests beyond standard specifications including endotoxin content, arsenic content, cell line testing, spectral analysis, and more. TOKU-E Company has custom manufacturing capabilities and is able to produce custom grade hygromycin B suitable for use in nearly all cell culture applications including use as an ancillary material for upstream pharmaceutical manufacturing. For more information, please contact us.
This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.
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For more information on hygromycin B, EvoPure®, click here.
CAS Number
31282-04-9
Molecular Formula
C20H37N3O13
Molecular Weight
527.52
Mechanism of Action
Hygromycin B inhibits protein synthesis by strengthening the interaction of tRNA binding in the ribosomal A-site. Hygromycin B also prevents mRNA and tRNA translocation by an unknown mechanism. These are unique mechanisms for an aminoglycoside antibiotic and they differ from the mode of action neomycin, gentamicin, and G418.
Storage Conditions
2-8°C
Tariff Code
2941.90.1010
Spectrum
Hygromycin B is effective against eukaryotic and prokaryotic cells.