• Anisomycin packaged and labeled.

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SKU: A021

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Description

Anisomycin is a sparingly soluble (2 mg/mL) protein synthesis inhibiting antibiotic produced by Streptomyces griseolus. Anisomycin targets eukaryotic cells and is not effective against bacteria (prokaryotes).
 

    CAS Number

    22862-76-6

    Molecular Formula

    C14H19NO4

    Molecular Weight

    265.30

    Mechanism of Action

    Anisomycin inhibits protein synthesis in eukaryotic cells by inhibiting peptidyl-transferase activity in the 60S subunit of the 80S ribosome.

    Storage Conditions

    2-8°C

    Tariff Code

    2941.90.1050

Specifications

    Form

    Powder

    Appearance

    White solid

    Source

    Streptomyces griseolus

    Water Content (Karl Fisher)

    ≤1.0%

    Melting Point

    141-143°C

    Assay

    (On Dried Basis): ≥98.0%

    Impurities

    Ethyl Acetate: ≤720ppm

References

    References

    Vazquez, David. "Anisomycin Binding to Eukaryotic Ribosomes." Journal of Molecular Biology 84.4 (1974): 603-23. ScienceDirect.com. 24 Apr. 1974. Web. 11 Sept. 2012.

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