Posaconazole is a synthetic, broad-spectrum, second generation triazole with antifungal activity. It has potent in vitro and in vivo trypanocidal activity. It was discovered by Schering-Plough and it is a structural analog of itraconazole. It has promising anti-cancer properties. Posaconazole is slightly soluble in DMSO but is practically insoluble in water.
