Omeprazole is an antacid compound which inhibits H+K+ ATPase and Carbonic Anyhdrase; both of which are responsible for gastric acid secretion. Omeprazole is sparingly soluble in water (0.823 mg/mL).
|Eukaryotic Cell Culture Applications||Omeprazole can be used in in vitro experiments when used against purified Carbonic Anhydrase and ATPase. Inhibitory effects of omeprazole against purified CA become apparent when used at 10-8 M and higher concentrations.|
|References||Puscas, Ioan, et al. "Omeprazole Has a Dual Mechanism of Action: It Inhibits Both H+K+ATPase and Gastric Mucosa Carbonic Anhydrase Enzyme in Humans (In Vitro and In Vivo Experiments)." The Journal of Pharmacology and Experimental Therapeutics 290.2 (1999): 530-34. Web. 11 Mar. 2013.|