Micronomicin Sulfate is the sulfate salt of Micronomicin, a natural aminoglycoside, broad-spectrum antibiotic discovered and developed by Kyowa Hakko Kogyo Co. The structure was determined as 6’-N-methylgentamicin C1a, and it is similar to Gentamicin C in physicochemical and antimicrobial properties but unlike Gentamicin C, it has remarkable activity against some gentamicin C1a-resistant strains. It targets Gram-positive and Gram-negative bacteria by interfering with bacterial protein synthesis. Micronomicin Sulfate is freely soluble in water.
|Mechanism of Action||Aminoglycoside antibiotics target the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.|
|Microbiology Applications||Micronomicin Sulfate is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options.|
|Spectrum||Micronomicin Sulfate has activity against Gram-positive and Gram-negative bacteria including S. aureus, S. epidermidis, E. coli, and P. aeruginosa.|
|Molecular Formula||C20H41N5O7 •2.5H2SO4|
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