SKU: M044  / 
    CAS Number: 235114-32-6


    $239.50 - $837.50

    Micafungin is a semi-synthetic cyclic lipopeptide antifungal belonging to the echinocandin class that was reported in 1999 from Fujisawa in Japan. Unlike other marketed semi-synthetic derivatives in this class, Micafungin is derived from FR901379, which contains a phenolic sulfate to enhance aqueous solubility, a serious limitation in the echinocandin class. 

    Micafungin is soluble in ethanol, methanol, DMF or DMSO. It has moderate water solubility.

    Mechanism of Action Micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
    Molecular Formula C56H71N9O23S

    Tawara S et al (2000)  In vitro activities of a new lipopeptide antifungal agent, FK463, against a variety of clinically important fungi.  Antimicrob. Agents Chemother. 44:57

    Tomishima M et al (1999)  FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activity. J. Antibiot. 52:674