SKU: M103  / 
    CAS Number: 2259-06-5

    Methyl Betulinate

    $121.50 - $422.50

    Methyl Betulinate is the methyl ester of Betulinic Acid, a pentacyclic lupane terpene isolated as a constituent of various tree species, including birch. In Australia, Methyl Betulinate was isolated from Akania bidwillii (syn. Akania lucens) by Ritchie and Taylor, University of Sydney in the late 1960s. More recently, Methyl Betulinate has been reported to be active in a number of bioassays, in particular against the malaria parasite, Plasmodium falciparum, and against human melanoma cell lines.

    Molecular Formula  C31H50O 

    Krajniak E et al (1969)  Some constituents of Akania lucens. Aust. J. Chem. 22:1331

    Sarek J et al (2011)  The potential of triterpenoids in the treatment of melanoma.  In: Research on melanoma - A glimpse into current directions and future trends DOI: 10.5772/19582

    Ziegler HL et al (2004)  Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: Structure-activity relationships for betulinic acid analogues. Bioorg. Med. Chem. 12:119