SKU: F014  / 
    CAS Number: 59-30-3

    Folic Acid, USP

    $30.50 - $392.00

    Folic Acid, USP (vitamin B9) and the resulting metabolites are essential to a number of organisms.  Folic Acid is slightly soluble in water and soluble in dilute acidic solutions and alkaline solutions.

    Mechanism of Action Cellular enzymes convert folic acid into dihydrofolic acid which is used as a precursor for a number of compounds including tetrahydrofolate (THF) which are involved in DNA repair and synthesis because of its role in purine synthesis.
    Microbiology Applications Folic Acid is frequently used in cell culture to provide tetrahydrofolates and other essential metabolites.
    Eukaryotic Cell Culture Applications Folic Acid has been used to research the influence of vitamins and amino acids on the growth of hybridomas and their influence on monoclonal antibody production.
    Molecular Formula C19H19N7O6
    Solubility Acid solutions (dilute): Soluble
    Alkaline solutions: Soluble
    Methanol: Slightly soluble
    Water: Slightly soluble

    Aaronson S and Rodriguez E (1958)  Relationship between purines Folic Acid-vitamins in the micrococcus, Gaffkya homari. 75(6):660-665

    Ducommun P, Ruffieux PA, von Stockar U and Marison I (2001)  The role of vitamins and amino acids on hybridoma growth and monoclonal antibody production. Cytotechnol. 37(2), 65–73  PMID 19002903