SKU: B039  / 
    CAS Number: 88899-56-3

    Bafilomycin B1

    $116.83 - $408.90
    Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.

    Bafilomycin B1 is soluble in ethanol, methanol, DMF and DMSO.
    Mechanism of ActionBafilomycin A1 is an inhibitor of vacuolar-type ATPase.
    ReferencesBafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al. Int. J. Parasitol. 1995, 25, 349. 

    Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al. Histol. Histopathol. 2007, 22, 443.