SKU: A125  / 
    CAS Number: 82189-03-5

    Ansatrienin A

    $163.50 - $571.00
    Ansatrienin A, isolated from a Streptomyces sp., is closely related to the cytotrienins and trienomycins. It displays potent activity against tumor cell lines and inhibits osteoclastic bone resorption. Ansatrienin A also significantly potentiates the action of several clinical anti-cancer agents.

    Ansatrienin A is soluble in ethanol, methanol, DMF and DMSO. 
    Molecular FormulaC36H48N2O8
    ReferencesMycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. , J. Biol. Chem. 1995, 270, 25949. 

    Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. , Gann. 1983, 74, 759. 

    Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. , J. Antibiot. 1982, 35, 1467.