Adenine 9-ß-D-arabinofuranoside (Vidarabine) is a purine nucleoside with anti-viral activity against some DNA viruses including herpesviruses and varicella zoster viruses.
|Mechanism of Action||Adenine 9-ß-D-arabinofuranoside (Vidarabine) inhibits DNA synthesis in DNA viruses by becoming incorporated into viral DNA and ultimately producing a faulty DNA sequence.|
|Spectrum||Adenine 9-ß-D-arabinofuranoside is active against poxviruses, herpesviruses, rhabdoviruses, and hepadnaviruses.|
|References||Pollard, R. B. "Effect of Vidarabine on Chronic Hepatitis B Virus Infection." JAMA: The Journal of the American Medical Association 239.16 (1978): 1648-650.|