SKU: A090  / 
    CAS Number: 59277-89-3

    Acyclovir (Acycloguanosine)

    $114.73
    Acyclovir (acycloguanosine) is a synthetic purine nucleoside analog and is used as an antiviral medication for the treatment of herpes simplex virus (HSV), shingles, and chickenpox.

    Synonyms: acycloguanosine, ACV, Zovirax, 9-[(2-Hydroxyethoxy)methyl]guanine
    Mechanism of ActionAcyclovir (acycloguanosine) is converted to acyclovir triphosphate (ACV-TP) by viral enzymes which inactivates HSV DNA polymerases.
    Spectrumacyclovir (acycloguanosine) targets most herpesvirus species including HSV-1, HSV-2, cytomegalovirus, Epstein-Barr virus (EBV), and Varicella zoster virus (VZV).
    Impurity Profile

    TLC: Not more than 0.5%
    HPLC, Guanine: Not more than 0.7%
    Single Impurity: Not more than 0.5%
    Total Impurities: Not more than 1.0%

    Molecular FormulaC8H11N5O3
    Impurity Profile

    TLC: Not more than 0.5%
    HPLC, Guanine: Not more than 0.7%
    Single Impurity: Not more than 0.5%
    Total Impurities: Not more than 1.0%

    ReferencesElion, Gertrude B. "Mechanism of Action and Selectivity of Acyclovir." American Journal of Medicine, 20 July 1982. Web.