Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp. It shows selective (>106 fold) and potent (MIC=0.0001 µg/ml) activity against Helicobacter pylori, the principal cause of peptic ulcer disease. Actinopyrone A was originally identified for its coronary vasodilating activity and weak activity against some Gram-positive bacteria and dermatophytes.
Actinopyrone A is soluble in ethanol, methanol, DMF and DMSO.
