• Zymosan A packaged and labeled.

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SKU: Z001

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Description

Zymosan A is a polysaccharide compound found on the surface of various fungi. Zymosan A has been found to bind to TLR2, a surface membrane receptor responsible for recognizing bacterial, viral, and fungal substances. Zymosan A is insoluble in water.

    CAS Number

    58856-93-2

    Molecular Formula

    (C6H10O5)x

    Molecular Weight

    Variable

    Mechanism of Action

    Zymosan A binds to and stimulates TLR2 (Toll-like receptor 2), a surface protein responsible for recognizing foreign substances such as cell wall components in pathogenic bacteria. Upon stimulation, TLR2 initiates a signaling cascade which eventually leads to specific immune responses.

    Storage Conditions

    2-8┬░C

    Tariff Code

    2938.90.0000

Applications

    Application

    Zymosan A can be used to study cytokine secretion and other immunologic properties in macrophages and dendritic cells (DCs).

Specifications

    Form

    Powder

    Source

    Saccharomyces cerevisiae

References

    References

    Dillon, Stephanie. "Yeast Zymosan, a Stimulus for TLR2 and Dectin-1, Induces Regulatory Antigen-presenting Cells and Immunological Tolerance." The Journal of Clinical Investigation 116.4 (2006): 916-28. Ncbi.gov. Web. 17 Apr. 2013.

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