SKU: T114

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Description
Trastuzumab is a recombinant humanized monoclonal antibody that is used in the treatment of cancer.

This product comes in a liquid form with a protein content of >15 mg/mL.

    CAS Number

    180288-69-1

    Molecular Formula

    ‎C6470H10012N1726O2013S42

    Molecular Weight

    145531.5

    Mechanism of Action

    HER2 is a receptor tyrosine kinase and epidermal growth factor which overexpresses in breast cancer cells causing over-proliferation. Trastuzumab targets the extracellular domain IV of HER2, keeping it from dimerizing and activating.

    Storage Conditions

    -20°C

Specifications

    Form

    Liquid

    Assay

    ≥97%

References

    References

    Vu, T., & Claret, F. X. (2012). Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer. Frontiers in Oncology, 2, 62. http://doi.org/10.3389/fonc.2012.00062

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