• Pneumocandin B0 packaged and labeled in glass vial.

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SKU: P092

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Description
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula.

Pneumocandin B0 is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    135575-42-7

    Molecular Formula

    C50H80N8O17

    Molecular Weight

    1065.2

    Mechanism of Action

    Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White to off white solid

References

    References

    671,329, a new antifungal agent I. Fermentation and isolation. Schwartz R. E. et al. J Antibiot. 1989, 42, 163.

    671,329, a new antifungal agent II. Structure determination Wichmann C. F. et al. J Antibiot. 1989, 42, 168.

    L-671,329, a new antifungal agent. III. In vitro activity, toxicity and efficacy in comparison to aculeacin. Fromtling R. A. & Abruzzo G. K. J. Antibiot. 1989, 42, 168.

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