• Moniliformin packaged and labeled in glass vial.

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SKU: M068

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Description
Moniliformin is a potent, water-soluble mycotoxin produced by several species of Fusarium. Comparative toxicity studies of moniliformin in chicken cell lines revealed no toxicity to chondrocytes and macrophages, but toxicity to splenocytes, cardiac and skeletal myocytes.

Moniliformin is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    71376-34-6

    Molecular Formula

    C4HNO3Na

    Molecular Weight

    120.0

    Mechanism of Action

    Moniliformin selectively inhibits mitochondrial oxidization of pyruvate and α-ketoglutarate, however the mode of action is not yet completely resolved.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Pale yellow powder

References

    References

    Comparative cytotoxicity of fumonisin B1 and moniliformin in chicken primary cell cultures. Wu W. et al. Mycopathologia 1995, 132, 111

    A molecular mechanism for the toxic action of moniliformin, a mycotoxin produced by Fusarium moniliforme. Thiel P. G. Biochem. Pharmacol. 1978, 27, 483.

    Moniliformin, a metabolite of Fusarium moniliforme NRRL 6322: purification and toxicity. Burmeister H. R. et al. Appl. Environ. Microbiol. 1979, 37, 11.

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