• Lenalidomide

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SKU: L044

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Description
Lenalidomide is an analogue of the immunomodulatory drug thalidomide with increased potency and fewer adverse effects. It is used in the treatment of hematologic and solid cancers due to its antitumor and anti-angiogenic activities.

    CAS Number

    191732-72-6

    Molecular Formula

    C13H13N3O3

    Molecular Weight

    259.26

    Mechanism of Action

    Lenalidomide has been shown to inhibit production of pro inflammatory cytokines TNF-α, IL-1, IL-6, IL-12 and elevate the production of anti-inflammatory cytokine IL-10.

References

    References

    Kotla, V., Goel, S., Nischal, S., Heuck, C., Vivek, K., Das, B., & Verma, A. (2009). Mechanism of action of lenalidomide in hematological malignancies. Journal of Hematology & Oncology, 2(1), 36. doi:10.1186/1756-8722-2-36

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