Lenalidomide

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Lenalidomide

SKU: L044

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Description

Lenalidomide is an analogue of the immunomodulatory drug thalidomide with increased potency and fewer adverse effects. It is used in the treatment of hematologic and solid cancers due to its antitumor and anti-angiogenic activities.

CAS Number

191732-72-6

Molecular Formula

C₁₃H₁₃N₃O₃

Molecular Weight

259.26

Mechanism of Action

Lenalidomide has been shown to inhibit production of pro inflammatory cytokines TNF-α, IL-1, IL-6, IL-12 and elevate the production of anti-inflammatory cytokine IL-10.

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Technical Data

References

Kotla, V., Goel, S., Nischal, S., Heuck, C., Vivek, K., Das, B., & Verma, A. (2009). Mechanism of action of lenalidomide in hematological malignancies. Journal of Hematology & Oncology, 2(1), 36. doi:10.1186/1756-8722-2-36