• Fidaxomicin packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: F025

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Fidaxomicin is a recently marketed antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones, isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.

Fidaxomicin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

    CAS Number

    873857-62-6

    Molecular Formula

    C52H74Cl2O18

    Molecular Weight

    1058.0

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al. J. Antibiot. 1975, 28, 247.

    Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. I. Production. Omura S. et al. J. Antibiot. 1986, 39, 1407.

    Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I.

    Taxonomy, fermentation and antibacterial activity. Theriault R.J. et al. J. Antibiot. 1987, 40, 567.

Other Items In This Category