• Emamectin B1a, EvoPure� packaged and labeled in glass vial.

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SKU: E033

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Description
Emamectin B1a is a semi-synthetic 4"-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4"-hydroxy moiety and reductive amination. The introduction of the methylamino group greatly enhances the insecticidal potency of the avermectin class. Emamectin B1a, as a benzoate salt, is the major component (>90%) of the commercial insecticide/acaricide, emamectin.

Emamectin B1a is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    CAS Number

    121124-29-6

    Molecular Formula

    C49H75NO13

    Molecular Weight

    886.1

    Mechanism of Action

    Members of the avermectin/milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Discovery of novel avermectins with unprecedented insecticidal activity. Mrozik H. et al. Experientia 1989, 45, 315.

    Synthesis of 4"-epi-amino-4"-deoxyavermectins B1. Cvetovich R.J. et al. J. Org. Chem. 1994, 59, 7704.

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