• Corynecin III, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: C186

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Corynecin III (methamphenicol) is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin III is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin III shows a similar species selectivity. Corynecin III was used as a bioisostere of chloroamphenicol to examine the binding relationship of chloramphenicols to DraE virulence factor.

Corynecin III is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    18048-95-8

    Molecular Formula

    C13H18N2O5

    Molecular Weight

    282.3

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Production of antibacterial compounds analogues to chloramphenicol by a n-paraffin-grown bacterium. Suzuki T. et al. Agri. Biol. Chem. 1972, 36, 2223.

    The structure of corynecins; chloramphenicol by a n-paraffin-grown bacterium. Shirahata K. et al. Agri. Biol. Chem. 1972, 36, 2229.

    A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol. Pettigrew D.M. et al. Acta Cryst. Set. D 2009, 65, 513.

Other Items In This Category