• Cephapirin benzathine

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SKU: C217

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Description
Cephapirin is a first-generation cephalosporin that boasts broad spectrum activity against gram-positive and gram-negative organisms. It is more resistance to beta-lactamases than the penicillin family. It is commonly used in the veterinary field.

Cephapirin benzathine is practically insoluble in water, ether, and toluene.

    CAS Number

    97468-37-6

    Molecular Formula

    C34H34N6O12S4 · C16H20N2

    Molecular Weight

    1087.27

    Mechanism of Action

    Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death.

References

    References

    CEPHAPIRIN (Veterinary—Intramammary-Local) (2003) The United States Pharmacopeial Convention, Inc. Monograph. American Academy of Veterinary Pharmacology and Therapeutics. Website.

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