• Beauvericin packaged and labeled in glass vial.

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SKU: B045

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Description
Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities.

Beauvericin is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    26048-05-5

    Molecular Formula

    C45H57N3O9

    Molecular Weight

    783.0

    Mechanism of Action

    At the molecular level, beauvericin exhibits ionophore properties, and inhibits acyl-CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White powder

References

    References

    The structure of beauvericin, a new depsipeptide antibiotic toxic to Artemia salina. Hamill Z. R. L. et al. Tet. Letters 1969, 4255. 

    Inhibition of acyl-CoA:cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. Tomoda H. et al. J. Antibiot. 1992, 45, 1626. 

    Beauvericin Production by Fusarium Species. Logrieco A. et al. Appl. Environ. Microbiol. 1998, 64, 3084.

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