• Aureothin packaged and labeled in glass vial.

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SKU: A134

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Description
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori.

Aureothin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.

    CAS Number

    2825-00-5

    Molecular Formula

    C22H23NO6

    Molecular Weight

    397.4

    Mechanism of Action

    Aureothin acts by inhibiting oxidoreductase.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Pale yellow solid

References

    References

    Gamma-pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M. et al. J Antibiot. 2000, 53, 844. 

    Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich T. et al. Eur J Biochem. 1994, 219, 691.

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