• Amygdalin (Vitamin B17) packaged and labeled.

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SKU: A066

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Description

Amygdalin (Vitamin B17) is a glucoside derived from almonds and apricot kernals and is structurally related to vitamin B17. In the 1950s, amygdalin was a proposed anti-cancer agent; however, because of its cyanogenic properties, its use is highly avoided. Amygdalin is freely soluble in water at 83 mg/mL.

    CAS Number

    29883-15-6

    Molecular Formula

    C20H27NO11

    Molecular Weight

    457.43

    Mechanism of Action

    After ingestion of amygdalin, β-glucosidase enzymes in the digestive system metabolize amygdalin producing hydrogen cyanide. Some of the hydrogen cyanide produced can find its way to tumor cells which is thought to have a potent cytotoxic effect.

    Storage Conditions

    2-8°C

    Tariff Code

    2936.29.5050

Applications

    Cancer Applications

    Amygdalin can be used to study cytotoxic effects of cyanide on cancerous cells.

Specifications

    Form

    Powder

    Appearance

    White Powder

    Source

    Almonds and apricot kernels

    Melting Point

    210-215°C

    Optical Rotation

    -40° to -45°

    Assay

    (HPLC): ≥98.0%

    Loss on Drying

    ≤5.0%

    Impurities

    Chloride: ≤20 ppm

References

    References

    Miazzo, S., et al. "Laetrile Treatment for Cancer." Cochrane Database of Systematic Reviews 9.11 (2011): n. pag. Ncbi.gov. Web. 5 Nov. 2012.

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