• 10'-desmethoxystreptonigrin packaged and labeled in glass vial.

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SKU: D048

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Description
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.

10'-Desmethoxystreptonigrin is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    136803-89-9

    Molecular Formula

    C24H20N4O7

    Molecular Weight

    476.1

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    Red Brown solid

References

    References

    10'-desmethyloxystreptonigrin, a novel analog of streptonigrin. Liu W.C. et al. J. Antibiot. 1992, 45, 454.

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