OP-145 (syn: (acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide) is a synthetic antimicrobial peptide (AMP) developed from the human cathelicidin LL-37. OP-145 consists of 24 amino acids and has demonstrated antibacterial and cytotoxic properties. It was synthesized by Shanghai Apeptide Co. Ltd. (Shaghai, China).
AMPs usually can accelerate immune defenses and wound healing ability in vivo, making them an alternative candidate to traditional antibiotics.