Antiparasitics

10,11-dehydrocurvularin

Dehydrocurvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including Curvularia, Penicillium and Alternaria. Dehydrocurvularin inhibits cell division by disrupting mitotic spindle...

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21-Hydroxyoligomycin A

21-Hydroxyoligomycin A is a rare member of the Oligomycin class, isolated as a co-metabolite of nemadectin, hence it was originally named Nemadectin omega. Only limited literature references are available. In-house testing suggests that...

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Albofungin

Albofungin is a polyaromatic heterocycle containing a rare N-aminoamide, isolated from a Streptomyces species in Russia in 1959. Albofungin exhibits a broad biological profile with antibiotic, antifungal, anthelmintic and very potent antitumor activity...

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Amodiaquine hydrochloride

Amodiaquine Hydrochloride is a synthetic,4-aminoquinoline compound with anti-malarial and anti-inflammatory properties.  It is a histamine-N-methyltransferase inhibitor that was developed in 1948.  Amodiaquine Hydrochloride is a congener of...

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Anagyrine

  Molecular Formula  C15H20N2O  

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Anhydroepiophiobolin A

Anhydroepiophiobolin A is a dehydrated analogue of ophiobolin epimerised at the C6 position. Anhydroepiophiobolin A is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many Bipolaris species. Prior to...

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Anhydroophiobolin A

3-Anhydroophiobolin A is the dehydrated analogue of ophiobolin A and is a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus Bipolaris. Like all ophiobolins, 3-anhydroophiobolin A possesses a broad...

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Antimycin

Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class,...

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Antimycin A1

Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes.Antimycin...

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Antimycin A2

Antimycin A2 is a homologue of the antimycin complex, first resolved from antimycin A1 in 1959. Antimycin A2, like all antimycins, is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A2 exhibits broad...

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Antimycin A3

Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Antimycin A3 exhibits broad biological activity as an...

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Antimycin A4

Antimycin A4 is the most polar of the major components of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A3. Antimycin A4 exhibits broad biological activity as an antifungal, anthelmintic,...

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