• Vitamin B12, USP packaged and labeled.

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SKU: V004

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Description

Vitamin B12 has the largest and most complicated structure of the B vitamins. Vitamin B12 is soluble in aqueous solution at 12.5 mg/mL.

    CAS Number

    68-19-9

    Molecular Formula

    C63H88CoN14O14P

    Molecular Weight

    1355.37

    Mechanism of Action

    Vitamin B12 is required for DNA synthesis as it serves as a precursor for the amino acid methionine. This is consistent with a finding that bacterial cells with a vitamin B12 deficiency have significantly less cellular DNA content. In addition, vitamin B12 is converted into s-adenosylmethionine, a broad spectrum methyl group donor for >100 different substrates including DNA, RNA, and a number of proteins.

    Storage Conditions

    2-8 °C

    Tariff Code

    2936.26.0000

Applications

    Microbiology Applications

    Because of its role in a number of essential cellular processes, vitamin B12 is frequently used as a cell culture media supplement.

Specifications

    Form

    Powder

    Appearance

    Pink or Red Powder

    Melting Point

    >392 °C

    Assay

    96.0-100.5

    Loss on Drying

    ≤12.0%

References

    References

    Iordan, E. P., and et al. "DNA Synthesis in Relation to a Varying Vitamin B12 Content in Propionibacterium Shermanii Cells." Mikrobiologiia 52.4 (1983): 591-96.www.ncbi.gov. Web. 31 Aug. 2012.

    "Vitamin B12 Fact Sheet." Office of Dietary Supplements. National Institutes of Health, 24 June 2011. Web. 31 Aug. 2012.

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