• Sulfadoxine (Sulphadoxine) packaged and labeled.

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SKU: S035

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Description

Sulfadoxine is a sulfonamide antibiotic frequently used for the treatment of malaria and bacteria that cause urinary and respiratory tract infections.  Sulfadoxine is also routinely used in combination for malaria infections when used in combination with pyrimethamine. Sulfadoxine is soluble in water and ethanol: 0.296 mg/mL and 20mg/mL respectively.

    CAS Number

    2447-57-6

    Molecular Formula

    C12H14N4O4S

    Molecular Weight

    310.33 g/mol

    Mechanism of Action

    Like most sulfonamides, sulfadoxine inhibits folic acid synthesis by acting as a competitive inhibitor of dihydropteroate synthetase, an enzyme found in the folic acid synthesis pathway.

    Storage Conditions

    -20 °C

    Tariff Code

    2935.00.4800

    Spectrum

    Sulfadoxine is a broad spectrum antibiotic targeting a wide range of Gram-positive and Gram-negative bacteria.

Specifications

    Form

    Powder

    Melting Point

    197 °C

References

    References

    Henry, Richard J. "The Mode of Action of Sulfonamides." Bacteriology Reviews (n.d.): 175-84. www.ncbi.gov. Web. 27 Aug. 2012.

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