• Erlotinib hydrochloride packaged and labeled.

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SKU: E017

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Description

Erlotinib hydrochloride is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is a tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

    CAS Number

    183319-69-9

    Molecular Formula

    C22H23N3O4

    Molecular Weight

    393.43

    Mechanism of Action

    Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor. Erlotinib specifically targets the EGFR tyrosine kinase ATP binding site, which is highly expressed and occasionally mutated in various forms of cancer. Erlotinib prevents EGFR homodimer formation, a conformational change required for signal transmittance.

    Storage Conditions

    2-8 °C

    Tariff Code

    2933.59.5300

Specifications

    Form

    Powder

    Appearance

    White or off-white powder

    Source

    Synthetic

    Melting Point

    223-228 °C

    Assay

    98.0-101.0%

    Loss on Drying

    ≤0.5%

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