• Cefteram packaged and labeled in glass bottle.

click on thumbnail to zoom
SKU: C102

Size  
Price: make selection(s)
Description

Cefteram is a third generation cephalosporin antibiotic.  Cefteram is freely soluble in methanol, ethanol, chloroform, and acetonitrile. In water, cefteram is essentially insoluble.

    CAS Number

    82547-58-8

    Molecular Formula

    C16H17N9O5S2

    Molecular Weight

    479.49 g/mol

    Mechanism of Action

    Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

    Storage Conditions

    -20 °C

    Tariff Code

    2941.90.5000

    Spectrum

    Like many third generation cephalosporins, cefteram is mostly active against gram negative bacteria especially those which cause meningitis and gonorrhea.

Specifications

    Form

    Powder

References

    References

    Georgopapadakou, N. H. "Mechanisms of Action of Cephalosporin 3'-quinolone Esters, Carbamates, and Tertiary Amines in Escherichia Coli." American Society for Microbiology 37.3 (1992): 559-65. Antimicrobial Agents and Chemotherapy. Web. 21 Aug. 2012.

Other Items In This Category