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Description
Ceftaroline fosamil is a cephalosporin antibiotic known as Teflaro in the US and Zinforo in Europe. It is active against methicillin-resistant Staphylococcus aureus (MRSA), respiratory pathogens, and Gram-positive bacteria. Currently, ceftaroline fosamil is being investigated for community-acquired pneumonia and complicated skin and skin structure infections.

    CAS Number

    400827-46-5

    Molecular Formula

    C24H25N8O10PS4

    Molecular Weight

    744.73

    Mechanism of Action

    Ceftaroline fosamil is a β-lactam antibiotic. It binds to penicillin-binding protein (PBP) which prevents the formation of the bacterial cell wall (CD, 2011).

    Storage Conditions

    -20°C

    Spectrum

    Ceftaroline fosamil is known for having a broad spectrum. It is effective against Gram-positive organisms, Gram-negative organisms, and Pseudomonas spp (Laudano, 2011).

References

    References

    C., D., C., D., & D. (2011). Ceftaroline: A New Cephalosporin with Activity Against Methicillin-Resistant Staphylococcus aureus (MRSA). Clinical Medicine Reviews in Therapeutics,1. doi:10.4137/cmrt.s1637

    Laudano, J. (2011). Ceftaroline fosamil: a new broad-spectrum cephalosporin. Journal of Antimicrobial Chemotherapy, 66(Supplement 3), pp.iii11-iii18.

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