• Bialaphos sodium packaged and labeled.

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SKU: B013

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Description

Bialaphos sodium is a freely soluble herbicide synthesized by Streptomyces hygroscopicus and Streptomyces viridochromeogenes.

This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.

    CAS Number

    71048-99-2

    Molecular Formula

    C11H21N3NaO6P

    Molecular Weight

    345.27

    Mechanism of Action

    Bialaphos acts as a prodrug by separating into individual subunits of alanylalanine and phosphinothricin. Phosphinothricin is toxic to cells by accumulating ammonia and inhibiting photosynthesis and glutamine synthesis.

    Storage Conditions

    2-8°C

    Tariff Code

    2941.90.5000

Applications

    Microbiology Applications

    Sobrero et al. used bialaphos sodium from TOKU-E to study its effects on oligopeptide transporters in a Sinorhizobium meliloti hfq mutant. "Quantitative Proteomic Analysis of the Hfq-Regulon in Sinorhizobium meliloti."

    Plant Biology Applications

    Bialaphos sodium has successfully been used in major cereal species transformation including (wheat, rice, maize, barley, sorghum, oat and rye). The ‘bar’ gene was in these cases successfully incorporated in the plant genome, together with the gene of interest. When Bialaphos was applied after the transformation process only plants which were successfully transformed will be able to survive this antibiotic product application. (Aragão, 2002).

Specifications

    Form

    Powder

    Appearance

    Pale orange-colored powder

    Source

    Streptomyces Griseochromogenes

    Assay

    (HPLC): ≥80.0%

    Loss on Drying

    ≤8.0%

References

    References

    Aragão F.J.L. and Brasileiro A.C.M. Positive, negative and marker-free strategies for transgenic plant selection. Braz. J. Plant Physiol., 14(1):1-10, 2002.

    Imai, S., and et al. "Conversion of Bialaphos to Other Oligopeptides Containing Phosphinothricin by Streptomyces Hygroscopicus." The Journal of Antibiotics 44.9 (1991): 1006-012. www.ncbi.gov. Sept. 1994. Web. 5 Sept. 2012.

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