Anacardic Acid

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Anacardic acid is a histone acetyltransferase (HAT) inhibitor that is derived from cashew shells. Anacardic acid is associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Anacardic acid is a common inhibitor of several clinically targeted enzymes such as NFκB kinase, histone acetyltransferase, lipoxygenase (LOX-1), xanthine oxidase, tyrosinase and ureases.

CAS Number

16611-84-0

Molecular Formula

C₂₂H₃₆O₃

Molecular Weight

345.8

Mechanism of Action

Anacardic acid is a HAT (Histone Acetyltransferase) inhibitor.

Storage Conditions

-20°C

Applications

Application

Anacardic acid has been used for tooth abscesses, acnce, tuberculosis, and MRSA.

Specifications

Technical Data

References

Satoh, M.,Takeuchi, N.,Fujita, T., et al. Synthesis of anacardic acids utilizing an annelation reaction of isoxazoles with ethyl acetoacetate. Chemical & Pharmaceutical Bulletin 46(10), 1501-1505 (1998).

Balasubramanyam, K.,Swaminathan, V.,Ranganathan, A., et al. Small molecule modulators of histone acetyltransferase p300. The Journal of Biological Chemisty 278(21), 19134-19140 (2003).